Preface
MALDI-TOF Mass Spectrometry
1. MALDI-TOF and LC-MS/MS: A Paradigm Shift from Research to Frontline Microbial Diagnostics; A Laboratory's Vision and Relentless Resolve to Help Develop and Implement this New Technology Amidst Formidable Obstacles
2. Criteria for Development of MALDI-TOF Mass Spectral Database
3. Applications of MALDI-TOF Mass Spectrometry in Clinical Diagnostic Microbiology
4. The Challenges of Identifying Mycobacterium to the Species Level using MALDI-TOF MS
Section A: Modifications of Standard Bruker Biotyper Method
Section B: ASTA’s MicroID System and its MycoMp Database for Mycobacteria
5. Transformation of Anaerobic Microbiology since the Arrival of MALDI-TOF-MS
6. The Potential of MALDI-TOF MS to Distinguish between Taxonomically Similar Species that Manifest Different Infections
7. Identification of Species in Mixed Bacterial Populations using MALDI-TOF MS
8. Microbial DNA Analysis byMALDI-TOF Mass Spectrometry
Section A:DNA Analysis of Viral Genomes using MALDI-TOF MS
Section B:Mass Spectral Analysis of Proteins of Nonculture and Cultured Viruses
9. Analysis of Yeast and Fungi using a Non-Commercial Database
10. Development and Application of MALDI-TOF MS for Detection of Resistance Mechanisms
11. Discrimination of Burkholderia, Brucellaspp and other Taxa at the Subspecies Level Using MALDI-TOF Mass Spectrometry
12. MALDI-TOF-MS Based Upon the Ribosomal Proteins Coding in S10 for Proteotyping
Tandem MS/MS based Approaches to Microbial Characterisation
13. Tandem Mass Spectrometry Analysis as an Approach to Delineate Genetically Related Taxa
14. Mapping of the Proteogenome of Clostridium difficile Isolates of Varying Virulence
15. Determination of Antimicrobial Resistance using Tandem Mass Spectrometry
16. Proteotyping: Tandem Mass Spectrometry and Proteomic Analysis of Pathogenic Microorganisms
17. Proteogenomics of Pseudomonas aeruginosa in Chronic Cystic Fibrosis Infections
18. Top-Down Proteomics in the Study of Microbial Pathogenicity
19. Tandem Mass Spectrometry in Resolving Complex Gut Microbiota Functions
20. Proteogenomics of Non-Model Microorganisms
21. Analysis of Mass Spectral Data for Species Identification and Typing of Microorganisms
Section A:The analysis of MALDI-TOF MS spectra using the BioNumerics software
Section B:Subtyping of Staphylococcus spp. based upon MALDI-TOF MS Data
Section C: Elucidating the Intra-Species Proteotypes of Pseudomonas aeruginosa from Cystic Fibrosis
(leitura online e APP)
